Canon PIXMA R4560 Ink Cartridges
Your PIXMA Home Office TR4560 uses the CL-646 / CL-646XL / PG-645 / PG-645XL cartridge series. This two-cartridge system consists of one dedicated black and one tri-colour ink, which contains cyan, magenta, and yellow. Because the colour cartridge is a combined unit, the depletion of a single shade requires a full replacement of the colour tank. This setup is common in home office environments where text printing is the priority, as the integrated printhead design ensures a fresh firing mechanism with every cartridge swap to maintain consistent document sharpens.
Choosing between genuine and compatible options
For users looking to manage home office expenses, we provide both original Canon and compatible alternatives. Under Australian Consumer Law, using compatible cartridges does not void your printer warranty. Our compatible PG-645XL and CL-646XL units are designed to meet the same physical specifications as the originals but at a lower price point. If you choose to go with compatibles, they are backed by a money-back guarantee for your peace of mind. You can read more about the differences in our genuine vs compatible guide.
How long these cartridges last in real use
The lifespan of your ink depends heavily on the content of your documents. Canon determines the page yield for these inkjet cartridges using the ISO/IEC 24711 standard, which involves printing a set of five standard pages until the ink is exhausted. While the standard PG-645 and CL-646 are suitable for occasional use, the XL versions offer significantly more ink for those printing multiple times a week.
| Cartridge Number | Type | Colour | Page Yield | Cost Per Page |
|---|---|---|---|---|
| PG-645 | Standard | Black | 180 | $0.14 |
| CL-646 | Standard | Colour | 180 | $0.17 |
| PG-645XL | High Yield | Black | 400 | $0.083 |
| CL-646XL | High Yield | Colour | 400 | $0.098 |
Cost Per Page = Total Cartridge Price ÷ Page Yield (at 5% coverage). Prices based on Genuine cartridges.
Managing your replacements and delivery
If your printing is mostly monochrome text, you will find yourself replacing the PG-645 black cartridge much faster than the colour. However, for those printing colour-heavy invoices or school projects, the CL-646 tri-colour cartridge may run out sooner. Bundle packs containing both cartridges are the most effective way to ensure you aren't left unable to print when one unit hits empty.
Free delivery applies on all orders over $99 (conditions apply). To ensure your home office stays productive, we ship daily from our distribution warehouses in Perth, Brisbane, Sydney, Melbourne, and Adelaide. For details on returns, please visit our returns policy.
Browse our full range of Canon ink cartridges.
Pro Tip
Since the CL-646 is a tri-colour cartridge, printing photos with heavy blue skies or specific branding will deplete one internal ink chamber faster than the others. Once one colour is gone, the whole cartridge must be replaced, even if the other two colours remain. To get the best value, try to balance your colour usage where possible.
Frequently Asked Questions
Can I install a PG-645XL if my printer came with a standard PG-645?
Yes, the XL and standard cartridges are the same physical size and fit into the same slot. The "XL" designation refers only to the volume of ink inside the cartridge, allowing for a higher page yield before a replacement is required.
Why does my TR4560 prompt me to replace the colour cartridge when I only print in black?
Even if you select "Grayscale" in your settings, the printer occasionally uses small amounts of colour ink for maintenance cycles and to keep the printhead nozzles primed. Additionally, some "rich black" settings pull ink from the colour cartridge to produce a deeper black tone on the page.
What happens if one colour runs out in the CL-646 tri-colour cartridge?
Because the cyan, magenta, and yellow inks are all housed in one unit, you cannot replace them individually. If the printer detects that any one of those three colours is empty, the entire CL-646 cartridge must be replaced to continue printing in colour.














