Canon imagePROGRAF GP-4600S Ink Cartridges
Shop ink cartridges for your Canon imagePROGRAF GP-4600S, which uses the Canon PFI-2100 ink cartridges series. Ink Depot has been supplying reliable consumables for this printer since Jun 2024. As a 44-inch large-format pigment inkjet printer designed for vivid poster production and high-end graphics, managing ink levels across high-volume runs requires strategic tank sizing. Our 4.8 Google rating reflects a long-standing track record of premium cartridge performance. Upgrading frequently used channels like PFI-2700MBK Matte Black or PFI-3700CO Chroma Optimiser to 700ml tanks reduces per-millilitre printing costs significantly.
How ink consumption scales across large-format runs
Large-format print coverage varies drastically depending on media choices and image density. Standard ISO testing yields do not account for full-bleed poster runs or heavy gloss coating. Canon measures pigment ink output under ISO/IEC 24711 standards for continuous printing.
Choosing the right tank capacity for production
For high-coverage poster graphics, upgrading key colours from standard 160ml (PFI-2100 and PFI-3100 series) or 330ml (PFI-2300 and PFI-3300 series) to 700ml PFI-2700 and PFI-3700 tanks lowers cost per millilitre during extended print runs. If you print primarily gloss or satin media, Chroma Optimiser depletion will align closely with primary ink channels. Orders ship fast from our local facilities in Sydney, Melbourne, Brisbane, Perth, and Adelaide. Free delivery applies on all orders over $99. Explore full warranty terms via our Returns policy or browse our complete Canon ink cartridges range.
Production Cartridge Planning
Because large-format pigment printers perform automatic sub-tank replenishment, replacing an empty ink cartridge during an active print job does not pause or ruin your media print.
Frequently Asked Questions
Can I mix different cartridge sizes (160ml, 330ml, 700ml) in the GP-4600S at the same time?
Yes. The Canon imagePROGRAF GP-4600S accepts 160ml (PFI-2100/3100), 330ml (PFI-2300/3300), and 700ml (PFI-2700/3700) tanks interchangeably in any slot. You can install a 700ml PFI-2700MBK Matte Black cartridge alongside a 160ml PFI-3100B Blue cartridge without issue.
Why does Chroma Optimiser deplete faster on glossy photo prints compared to matte media?
Chroma Optimiser (PFI-3100CO, PFI-3300CO, PFI-3700CO) is a clear clear-coat layer applied over pigment inks to clear surface bronzing and equalise gloss reflection. When printing on matte paper, the printer automatically bypasses or reduces Chroma Optimiser output, whereas gloss and satin media trigger full surface coverage.
How does the sub-tank system work when replacing an ink cartridge mid-job?
The imagePROGRAF GP-4600S features internal sub-tanks between the main cartridge slots and the printhead. When a main ink cartridge reports empty, ink continues drawing from the internal sub-tank reserve, allowing you to swap out the empty tank mid-print without interrupting the print run or wasting roll paper.












































